DE Online Desk
I think the most common cause is hypertension, which destroys the glomeruli (blood-filtering capillary beds) of the kidneys.
Next to that, probably renal atherosclerosis—the buildup of fatty plaque in the renal arteries, cutting down the blood supply to the kidneys and starving them.
Glomerulonephritis is a kidney-destroying autoimmune disease, found in around 0.2 to 2.5 out of every 100,000 people worldwide. That’s rare, but in a high-density area like New York City or Los Angeles, that could mean up to 150 people or so with this disease at any one time.
Systemic lupus erythematosus (SLE), another multifaceted autoimmune disease, often causes glomerulonephritis and can lead to end-stage renal failure.
Other causes include chronic or repetitive kidney infections; diabetes mellitus; alcoholism; trauma (blows to the back, or frequent vibration, such as from heavy machinery but also habitual motorcycle or horseback riding); poisoning (heavy metals, carbon tetrachloride, acetone, paint thinners); and blockage of the renal tubules by proteins (as in some wasting muscle diseases, muscle injuries like compartment syndrome, and hemolysis (red blood cell breakdown) due to mismatched blood transfusions).
What are the causes of human kidney failure?
Leave a comment